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Hypercortisolism Is Associated With Increased Coronary Arterial Atherosclerosis

Hypercortisolism Is Associated With Increased Coronary Arterial Atherosclerosis: Analysis of Noninvasive Coronary Angiography Using Multidetector Computerized Tomography Journal of Clinical...

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A Subtle Case of Cushing’s

English: “Dr. Harvey Cushing,” oil on canvas, by the American artist Edmund Tarbell. Courtesy of the Dittrick Medical History Center. (Photo credit: Wikipedia) Synopsis: 36 year old male who presented...

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Pasireotide for the treatment of Cushing’s disease

Posted online on June 17, 2013. (doi:10.1517/21678707.2013.807731) Annamaria Colao †, Chiara Simeoli , Monica De Leo , Alessia Cozzolino , Rosario Pivonello Department of Clinical Medicine and Surgery,...

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Cushing’s Disease – Rare Disease Quick Facts

    Cushing’s disease is a rare condition due to excess cortisol levels that result from a pituitary tumor secreting adrenocorticotropic hormone (ACTH), which stimulates cortisol secretion.  Cushing’s...

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When to think Cushing’s syndrome in type 2 diabetes

ESTES PARK, COLO. – Diabetes mellitus, osteoporosis, and hypertension are conditions that should boost the index of suspicion that a patient with some cushingoid features may in fact have endogenous...

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Cyclic Cushing’s syndrome: a clinical challenge

J R Meinardi1,2, B H R Wolffenbuttel2 and R P F Dullaart2 +Author Affiliations 1Department of Internal Medicine, Canisius Wilhelmina Ziekenhuis, PO Box 9015, 6500 GS Nijmegen, The Netherlands and...

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NIH: An Open-Label Study of The Safety, Pharmacokinetics and Pharmacodynamics...

This study is currently recruiting participants. Summary Number 13-CH-0170 Sponsoring Institute National Institute of Child Health and Human Development (NICHD) Recruitment Detail Type: Participants...

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No High-Quality Studies for Cushing’s Drugs

By Salynn Boyles, Contributing Writer, MedPage Today Reviewed by Zalman S. Agus, MD; Emeritus Professor, Perelman School of Medicine at the University of Pennsylvania and Dorothy Caputo, MA, BSN, RN,...

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Genetic mutation lowers obesity in Cushing’s syndrome

London E. J Clin Endocrinol Metab. 2013; doi:10.1210/jc.2013-1956. Among adult patients with Cushing’s syndrome, those with mutations in PRKAR1A, the gene that controls cAMP-dependent protein kinase,...

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Think Like a Doctor: Red Herrings Solved!

By LISA SANDERS, M.D. On Thursday we challenged Well readers to take the case of a 29-year-old woman with an injured groin, a swollen foot and other abnormalities. Many of you found it as challenging...

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Skeletal Maturation in Children With Cushing’s Syndrome is Not Consistently...

Skeletal maturation in children with cushing syndrome is not consistently delayed: The role of corticotropin, obesity, and steroid hormones, and the effect of surgical cure. J Pediatr. 2014 Jan 9. pii:...

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Salivary cortisol performs better than urinary free cortisol to diagnose...

Late-night salivary cortisol has a better performance than urinary free cortisol in the diagnosis of Cushing’s syndrome. Salimetrics highlights a recent study:  Abstract Context: The comparison of...

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What would Harvey Cushing say about Cushing’s disease today?

(BPT) – More than 80 years ago renowned neurosurgeon, Dr. Harvey Cushing, discovered a tumor on the pituitary gland as the cause of a serious, hormone disorder that leads to dramatic physical changes...

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Cushing’s Awareness Challenge, Day 7

A Cushing’s diagnosis can be a long and frustrating event with testing, repeat testing, redoing testing. Sometimes, I think that this was the path that some of my UFCs took on the way to my diagnosis:...

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Cushing’s Awareness Challenge: Day 9

Another of Robin’s fine awareness graphics.  I had all these symptoms except Type 2 Diabetes. After my pituitary surgery, I had diabetes mellitus for a while but that went away. It was the easy...

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Use late-night salivary cortisol to catch recurrent Cushing’s

By: M. ALEXANDER OTTO, Clinical Endocrinology News Digital Network JULY 3, 2014 AT ICE/ENDO 2014 CHICAGO – Late-night salivary cortisol exceeded normal limits in 10 women with recurrent Cushing’s...

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Myth: UFC’s are the Gold Standard for Cushing’s testing

Myth: UFC’s are the Gold Standard for Cushing’s testing Fact: UFC stands for Urinary Free Cortisol. In layman’s terms this test assesses cortisol by collecting urine for 24 hours. It was once thought...

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Does a normal urine free cortisol result rule out Cushing’s syndrome?

  March 07, 2015 SAT 379-412-Cushing’s Syndrome Does a normal urine free cortisol result rule out Cushing’s syndrome? ST Sharma, LK Nieman Summary: Researchers conducted this study to assess the...

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Day Twenty, Cushing’s Awareness Challenge 2015

And today, we talk about pink jeeps and ziplines… How in the world did we get here in a Cushing’s Challenge?  I’m sliding these in because earlier I linked (possibly!) my growth hormone use as a cause...

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Interview May 13 with Michelle B (MichelleB), Cyclic Cushing’s Patient

Hello all, I’m Michelle mother of 3 beautiful children, I work part-time, 33yrs young, non-smoker, non-drinker, overall health is good for the most part…..Where do I even begin. I just recently...

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